Techniques in Regional Anesthesia & Pain Management
Volume 13, Issue 1 , Pages 5-8, January 2009

An introduction to migraine pathophysiology

  • Dyveke Pratt Benoit, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Dyveke Pratt Benoit, MD, Department of Neurology, Boston University, 72 East Concord Street, Boston, MA 02118

Department of Neurology, Boston University, Boston, Massachusetts

The pathophysiology of migraine is a complicated one. What produces aura, pain, and concurrent neurological symptoms is not completely clear. What we do know, however, is that migraine is a primary neurological disorder with effects throughout the body. In this article, we will review basic physiology of headache, characteristics of migraine, and more specifically, what is currently known about its pathophysiology.

Keywords: Migraine, Cortical spreading depression, Trigeminovascular system, Aura, Headache

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PII: S1084-208X(09)00011-1

doi:10.1053/j.trap.2009.04.002

Techniques in Regional Anesthesia & Pain Management
Volume 13, Issue 1 , Pages 5-8, January 2009